Multimodality “focuses on the design of discourse by investigating the contributions of specific semiotic resources (e.g. language, gesture, images) co-deployed across various modalities (e.g. visual, aural, somatic), as well as their interaction and integration in constructing a coherent text.” Source: Lim, F. V. , K.L. O’Halloran, S. Tan and M.K.L. E (2015: 917), ‘Teaching Visual Texts with Multimodal Analysis Software’, Educational Technology Research and Development 63(6), 915–935.
The range of complications of renal transplantation can be organized temporally in relation to the time since surgery and/or according to disease categories, including immunologic (rejection), surg...
PET-MRI: a review of challenges and solutions in the development of integrated multimodality imaging, Stefaan Vandenberghe, Paul K Marsden
What is the different between Language Acquisition and Language Learning? This is such a common question. Here we dive into all of it!
Augmenting Realities-How We View and Shape our World
Meet the first version of Gemini — our most capable AI model. Gemini is built from the ground up for multimodality — reasoning seamlessly across text, images, video, audio, and code.
Multifunctional nanoparticles with combined diagnostic and therapeutic functions (so called theranostics) show great promise towards personalized nanomedicine. However, attaining consistently high performance of these functions in vivo in one single nanoconstruct remains extremely challenging. A group of scientists now demonstrate the use of one single polymer to develop a smart ‘all-in-one’ nanoporphyrin platform that conveniently integrates a broad range of clinically relevant functions. Nanoporphyrins can be used as amplifiable multimodality nanoprobes for near-infrared fluorescence imaging (NIRFI), magnetic resonance imaging (MRI), positron emission tomography (PET) and dual modal PET-MRI. Nanoporphyrins greatly increase the imaging sensitivity for tumor detection through background suppression in blood, as well as preferential accumulation and signal amplification in tumors. Nanoporphyrins also function as multiphase nanotransducers that can efficiently convert light to heat inside tumours for photothermal therapy (PTT), and light to singlet oxygen for photodynamic therapy (PDT). Furthermore, nanoporphyrins act as programmable releasing nanocarriers for targeted delivery of drugs or therapeutic radio-metals into tumors.essica Tucker, program director of Drug and Gene Delivery and Devices at the National Institute of Biomedical Imaging and Bioengineering, which is part of the National Institutes of Health, said the approach outlined in the study has the ability to combine both imaging and therapeutic applications in a single platform, which has been difficult to achieve, especially in an organic, and therefore biocompatible, vehicle."This is especially valuable in cancer treatment, where targeted treatment to tumor cells, and the reduction of lethal effects in normal cells, is so critical," she added.Though not the first nanoparticles, these may be the most versatile. Other particles are good at some tasks but not others. Non-organic particles, such as quantum dots or gold-based materials, work well as diagnostic tools but have safety issues. Organic probes are biocompatible and can deliver drugs but lack imaging or phototherapy applications. | Amazing Science
