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nakimedicalblog - Posts tagged immunology
Immunology Cartoon Cells – DC
Eosinophils, multifunctional cells that contribute to both innate and adaptive immunity, are involved in the initiation, propagation, and resolution of immune responses, including tissue repair. They achieve this multifunctionality by expression of a diverse set of activation receptors, including those that directly recognize pathogens and opsonized targets, and by their ability to store and release preformed cytotoxic mediators that participate in host defense, to produce a variety of de novo pleotropic mediators and cytokines, and to interact directly and indirectly with diverse cell types, including adaptive and innate immunocytes and structural cells. Herein, we review the basic biology of eosinophils and then focus on new emerging concepts about their role in mucosal immune homeostasis, particularly maintenance of intestinal IgA. We review emerging data about their development and regulation and describe new concepts concerning mucosal eosinophilic diseases. We describe recently developed therapeutic strategies to modify eosinophil levels and function and provide collective insight about the beneficial and detrimental functions of these enigmatic cells.
Reproductive Immunology - Locus Medicus
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Amazon.com: Kuby Immunology: 9781464189784: Punt, Jenni, Stranford, Sharon, Jones, Patricia, Owen, Judy: Books
This is a hypothetical textbook cover design for an immunology textbook, showing a macrophage engulfing bacteria.
Mycobacterium tuberculosisObligate human pathogen.Approximately 1/3 of the world population is infected, and there are 8-10 million new cases each year. – Of these, 5-10% will develop tuberculosis disease, which kills 1-4 million people annually. Individuals with HIV or other immune deficiencies are more likely to develop severe infection; because of this, co-infection with HIV and tuberculosis is a major public health concern in areas where both infections are endemic. Transmitted from human to human via respiratory aerosols.Microbes are inhaled and travel to the lungs, where they are engulfed by alveolar phagocytes.Mycobacterium tuberculosis has evolved to highjack the innate immune response and to delay the adaptive immune response. – Disease development is the outcome of host and bacterial interactions that produces chronic inflammation. Primary InfectionOccurs when a new host first encounters Mycobacterium tuberculosis.Alveolar macrophages engulf Mycobacterium tuberculosis bacteria and sequesters the bacteria within a vacuole. – Recall that part of the innate immune response involves phagocytosis of microbes, followed by phago-lysosome fusion to expose the microbes to bactericidal lysozymes.Mycobacterium tuberculosis prevents phago-lysosome fusion, thus evading destructive enzymes. – Allows fusion with nutrient-filled vesicle to facilitates its own replication within the macrophage.Infected macrophage responds by secreting IL-12 and Tumor Necrosis Factor alpha (TNF-alpha).These cytokines recruit other immune cells to the area: – Natural killer cells, CD4+ T cells, and Monocytes. The CD4+ T cells differentiate to become Helper T cells that release Interferon gamma, which is a cytokine that activates macrophages.Interferon gamma triggers the following antibacterial effects: Phagolysosome maturation, production of oxygen reactive species and nitric oxide, antimicrobial defensin recruitment, autophagy, and macrophage differentiation to form epithelioid ce...
Award-winning custom medical illustration with over 25 years experience. Specializing in images showing Mechanism of Action, Anatomy, Surgical procedures, Immunology, and Patient Education.
Which one is your favorite? Cartoons by www.daisychung.com/immunology-cartoon-project-
Amount: 15,000 - Deadline: December 7, 2025 - The AbbVie Immunology Scholarship aims to reduce the financial burden for students impacted by
This Digital Prints item by PapaLeoArts has 128 favorites from Etsy shoppers. Ships from United States. Listed on Jan 19, 2025
Recent molecular investigations have significantly developed our knowledge of the characteristics of the reproductive microbiome and their association…
Nerdcore Medical and Tabletop Whale created this handy and informative graphic of all the important concepts in immunology. It's part of a series of one-pagers on topics of interest to…
