Some people with Vascular Ehlers-Danlos syndrome have a noticeable characteristic appearance, while others don't have any outward signs at all.

Have you recently been diagnosed with Ehlers-Danlos syndrome but still have symptoms that don’t appear to be directly related? Do you have a friend who is incre

Ehlers-Danlos syndrome (EDS) is a group of inherited connective tissue disorders that affect your body's ability to produce collagen. Collagen is a protein that gives elasticity and strength to your joints, skin, muscles, organs, blood vessels, and ligaments.

Do you experience these symptoms?

"People often blush when I bring that up..."

Ehlers-Danlos syndrome (EDS) is a group of disorders that affect connective tissues, such as: tissues that support the skin, bones, blood vessels, and other organs (2014, Genetics Home Reference). It is estimated that about 1 in 5,000 individuals worldwide suffer from EDS (Genetics Home Reference, 2014).

For those of you interested in the overlap between Ehlers-Danlos (EDS)/hypermobility spectrum disorders (HSD) and autism, sensory issues in EDS/HSD probably come as no great surprise. Nevertheless,…

What Is Ehlers-Danlos Syndrome? Ehler-Danlos syndrome is a group of rare inherited disorders that affect the body’s connective tissues, especially the

"I always thought I was just clumsy."

This isn’t going to be a post on how specifically to diagnose the Ehlers-Danlos syndromes (EDS) or Hypermobility Spectrum Disorders (HSD) per se, as that’s already been covered here. Rather, I want to draw attention to the many “red herrings” or false leads that we and our doctors often identify and manage to recognize and […]

Recent studies are showing a connection between this disease trifecta, Mast Cell Activation Syndrome (MCAS), Postural Orthostatic Tachycardia Syndrome (POTS), and Ehlers-Danlos Syndrome (EDS)

Original Editors - Corey Vogt from Bellarmine University's Pathophysiology of Complex Patient Problems project.

EDS is a complex illness and can cause many serious physical issues beyond simply "being flexible."

Ehlers-Danlos syndrome (EDS), postural orthostatic tachycardia syndrome (POTS), and mast cell activation syndrome (MCAS) are inter-related diseases.

Discover effective treatments for Ehlers Danlos Syndrome (EDS): relief from pain, joint support, and improved quality of life.

For those of you interested in the overlap between Ehlers-Danlos (EDS)/hypermobility spectrum disorders (HSD) and autism, sensory issues in EDS/HSD probably come as no great surprise. Nevertheless,…

"I always feel like running away right after."

In recent years, an association between hypermobile Ehlers-Danlos syndrome (hEDS), mast cell activation syndrome (MCAS), and postural orthostatic tachycardia syndrome (POTS) has garnered attention and patients are increasingly presenting with this triad. However, a real relationship between these entities is unclear due to a lack of scientific validity. We conducted an extensive review of the literature using two different search strategies. A narrower strategy included 88 searches of various combinations of terms for each of the three conditions, yielding 19 unique papers. A broader search included 136 searches of various combinations of terms but included all forms of EDS and yielded 40 unique papers. Of these, only four and nine papers from the narrower and broader search strategies were original research articles. None of these papers resulted from a combination of the search terms for the three conditions. All three clinical entities are controversial in either existence or pathogenesis. MCAS is a poorly defined clinical entity, and many studies do not adhere to the proposed criteria when establishing the diagnosis. Patients previously diagnosed with EDS hypermobility type may not meet the new, stricter criteria for hEDS but may for a less severe hypermobility spectrum disorder (HSD). The pathophysiology of POTS is still unclear. An evidence-based, common pathophysiologic mechanism between any of the two, much less all three conditions, has yet to be described. Our review of the literature shows that current evidence is lacking on the existence of MCAS or hEDS as separate or significant clinical entities. Studies proposing a relationship between the three clinical entities are either biased or based on outdated criteria. The reason behind the purported association of these entities stems from an overlapping pool of vague, subjective symptoms, which is inadequate evidence to conclude that any such relationship exists.

For over 25 years, we have successfully treated the symptomology of Ehlers-Danlos syndrome, hypermobility type (hEDS) using natural holistic interventions.

Dietary and nutritional supplement general guidelines for persons with Ehlers-Danlos syndrome, by Dr. Heidi A. Collins.

"In hindsight there were signs of EDS from my earliest memories."

These products help our community relieve pain and deal with joint hypermobility.

Our community didn't expect these things to help — but they did!

"Knowing all I know about EDS now I cannot believe they missed the signs..."

Is this what EDS looks like for you, too?

For those of you interested in the overlap between Ehlers-Danlos (EDS)/hypermobility spectrum disorders (HSD) and autism, sensory issues in EDS/HSD probably come as no great surprise. Nevertheless,…