CLL is usually a slow-growing cancer. Find out what you can do if it progresses.
In chronic lymphocytic leukemia (CLL), a person’s bone marrow makes too many lymphocytes, a type of white blood cell. Although rare, CLL can metastasize (spread) to the brain and the fluid lining the brain in what is called meningeal carcinomatosis.
Learn about how long, on average, you'll live with chronic lymphocytic leukemia based on your CLL type and how treatments can help extend your life.
Chronic lymphocytic leukemia (CLL) is a slow-growing cancer. Many people have no symptoms at diagnosis, but, over time, they may notice fatigue and other changes.
Chronic Lymphocytic Leukemia (CLL) is the most common type of leukemia in the Western world. CLL occurs mainly in the older population.
Chronic lymphocytic leukemia (CLL) is a type of cancer that affects the blood and bone marrow. Survival rates are typically good. Learn more here.
Small lymphocytic lymphoma (SLL) is the lymphoma (lymph nodes) form of chronic lymphocytic leukemia (CLL). Both CLL and SLL are indolent (slow-growing) bl
There are many different treatment options for chronic lymphocytic leukemia (CLL), a blood cancer that starts in the bone marrow. For older people or those
CLL stands for chronic lymphocytic leukemia. Chronic means it is a slower progressing disease, lymphocytic stands for the cancer cells may be present in...
See what to expect with the stages of chronic lymphocytic leukemia or CLL and how it is treated.
Chronic Lymphocytic Leukemia Clinical Trials are research studies aimed at increasing the quality of life and survival rate of patients.
When it comes to CLL symptoms, what’s fact and what’s fiction? Dr. Kerry Rogers reviews CLL symptoms and discredits common myths.
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There may be a connection between diet and chronic lymphocytic leukemia (CLL). Learn what foods to eat and avoid to better manage your CLL.
Chronic lymphocytic leukemia, or CLL, is a slow-growing cancer of the blood and bone marrow. It is the most common type of adult leukemia.
Fatigue is one of the most common symptoms experienced by those living with CLL and SLL, and it is also commonly overlooked, and underreported.
There may be a connection between diet and chronic lymphocytic leukemia (CLL). Learn what foods to eat and avoid to better manage your CLL.
Slow-growing chronic lymphocytic leukemia may not need treatment right away. Learn what to expect from a CLL watchful waiting approach.
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When Carol's cat Sage, an 11- year old, was diagnosed with CLL/SLL, this cat mom decided to take the natural route with NHV's Cancer Detox Kit.
Chronic lymphocytic leukemia (CLL) is the most common leukemia diagnosed in adults. What sets CLL apart from other leukemia types include where it starts and how fast it usually grows.
Partners in Science 2.0 to train science teachers alongside Fred Hutch researchers making leading-edge advances in cancer research.
Many treatments are available for chronic lymphocytic leukemia, and recent breakthroughs and clinical trials are under investigation. Learn about your options.
Patients with chronic lymphocytic leukemia (CLL) who feel more stress also have more cancer cells in their blood and elevated levels of three other markers of more advanced disease. A new study of 96 patients is the first to link stress with biological disease markers in patients with CLL. “All four variables we measured are related to pro...
Chronic lymphocytic leukemia (CLL) is a blood cancer characterized by abnormal lymphocyte accumulation. Causes are unknown, and symptoms include fatigue and swollen lymph nodes. CLL diagnosis involves blood tests and biopsies. Treatments vary based on disease stage, with outcomes ranging from observation to therapy. 6 Must Tests for CLL Diagnosis Accurate CLL diagnosis is crucial in Chronic Lymphocytic Leukemia (CLL) to determine the stage, guide treatment decisions, and monitor disease progression, improving patient outcomes and quality of life. In the chronic lymphocytic leukemia diagnosis, various tests may be performed to evaluate the condition. Here is a list of common tests used: Complete Blood Count (CBC) Flow Cytometry Immunophenotyping Bone Marrow Aspiration and Biopsy Cytogenetic Analysis Fluorescence In Situ Hybridization (FISH) 1. Complete Blood Count (CBC) Comprehensive analysis of blood components for CLL diagnosis. Accurate evaluation of red and white blood cell counts. Assessment of hemoglobin levels for oxygen-carrying capacity. Category Details Also Known As Hemogram, Full Blood Count (FBC) Purpose Assess overall health, detect blood disorders Sample Blood sample Preparation None Procedure Blood draw from a vein Test Timing 2-4 hours Test Price (INR) 300-800 Result Value Quantitative measurement of blood components Normal Value Varies based on age, gender, and other factors Accuracy High Interpretation Evaluated by healthcare professionals based on specific needs In CLL diagnosis, Complete Blood Count (CBC) test assesses overall health, detects disorders/infections. Quick, accurate, and widely available at an affordable price. 2. Flow Cytometry Precise cellular analysis using powerful technology. Quantification of cell populations with high accuracy. Identification of specific cell types for CLL diagnosis purposes. Category Details Also Known As Immunophenotyping Purpose Analyze cell populations Sample Blood, bone marrow, or bodily fluids Preparation Depends on the specific sample type Procedure Cell staining & analysis using a flow cytometer Test Timing Same day results Test Price (INR) 2,000-6,000 Result Value Identification of cell types Normal Value Varies based on specific cell populations Accuracy High Interpretation Assessed by medical professionals based on context Flow Cytometry (Immunophenotyping) accurately analyzes cell populations for various samples, providing valuable CLL diagnosis insights. Quick results available (INR 2,000-10,000) with high accuracy and interpretation by medical professionals. 3. Immunophenotyping Accurate identification and characterization of specific immune cell types. Evaluation of cell surface markers to understand immune system function. Precise detection and classification of abnormal cells for chronic lymphocytic leukemia diagnosis and monitoring. Category Details Also Known As Flow Cytometry Purpose Identify immune cell types Sample Blood, bone marrow, bodily tissues Preparation Depends on the sample type Procedure Cell staining & analysis using a flow cytometer Test Timing Usually same day results Test Price (INR) 2,000-10,000 Result Value Characterization of immune cells Normal Value Varies on specific immune cell populations Accuracy High Interpretation Assessed by medical professionals based on context Immunophenotyping (Flow Cytometry) identifies and characterizes immune cell types in samples like blood or tissue. Quick results available (INR 2,000-10,000) with high accuracy, aiding in CLL diagnosis and medical interpretation. 4. Bone Marrow Aspiration and Biopsy Diagnostic procedure for evaluating bone marrow health and detecting abnormalities. Collection of bone marrow samples for microscopic examination and genetic analysis. Accurate CLL diagnosis of hematopoietic cells, identifying blood disorders and malignancies. Category Details Also Known As Bone Marrow Examination Purpose Assess bone marrow health & blood disorders Sample Bone marrow from hip bone Preparation None Procedure Extracting liquid marrow Test Timing A few days Test Price (INR) 3,000-8,000 Result Value Microscopic examination Normal Value Varies based on age, gender Accuracy High Interpretation Assessed by healthcare professionals based on specific needs Bone Marrow Aspiration and Biopsy test evaluates bone marrow health, detects abnormalities, and blood disorders. Quick and accurate chronic lymphocytic leukemia diagnosis results (INR 3,000-8,000) aid medical interpretation by professionals. 5. Cytogenetic Analysis Detailed examination of chromosomes to detect genetic abnormalities and chromosomal rearrangements. Identification of specific genetic mutations and alterations related to various diseases. Precise CLL diagnosis for personalized treatment planning and prognosis assessment. Category Details Also Known As Chromosome Analysis Purpose Detect genetic abnormalities, chromosomal rearrangements Sample Blood, bone marrow, or tissue samples Preparation Depends on the sample type Procedure chromosomes microscopy & genetic techniques Test Timing A few days Test Price (INR) 5,000-15,000 Result Value Identification of genetic mutations, chromosomal alterations Normal Value Varies based on genetic markers Accuracy High Interpretation Assessed by medical professionals based on specific needs In CLL diagnosis, Cytogenetic Analysis detects genetic abnormalities and rearrangements. Results (INR 5,000-15,000) aid interpretation of genetic mutations and chromosomal alterations by medical professionals. 6. Fluorescence In Situ Hybridization (FISH) Utilizes fluorescent probes to detect specific DNA sequences and chromosomal abnormalities. High sensitivity and specificity for identifying genetic alterations associated with diseases. Aids in chronic lymphocytic leukemia diagnosis, prognosis, and treatment decisions for various genetic disorders and cancers. Category Details Also Known As FISH Purpose Detect specific DNA sequences Sample Cell Sampling Preparation Depends on the sample type Procedure DNA probe binding to specific sequences Test Timing A few days Test Price (INR) 5,000-15,000 Result Value Identification of specific DNA sequences Normal Value Varies on specific genetic markers Accuracy High Interpretation Assessed by medical professionals based on specific needs Fluorescence In Situ Hybridization (FISH) test detects specific DNA sequences and chromosomal abnormalities. Results (INR 5,000-15,000) aid interpretation by identifying genetic markers accurately and reliably. Chronic Lymphocytic Leukemia Tests Overview Test Name Complete Blood Count (CBC) Flow Cytometry Immunophenotyping Also Known As Hemogram, Full Blood Count Immunophenotyping Flow Cytometry Purpose Detect blood disorders & infections Identify different cell populations Determine cell markers for CLL diagnosis Sample Preparation Blood sample in EDTA tube Blood or bone marrow sample Blood or bone marrow sample Procedure Automated blood analyzer Flow cytometry analysis Flow cytometry analysis Test Timing 2-4 hours Same day results Same day results Test Price (INR) 300-800 2,000-10000 2,000-6,000 Result Value Quantitative measurement of blood components Identification of cell types Characterization of immune cells Normal Value Varies by age Varies Varies Accuracy High High High Interpretation Evaluated by healthcare professionals based on specific needs Assessed by medical professionals based on context Assessed by medical professionals based on context *Test Price, range, and timing may vary as per location, lab type, and procedure. Complete Blood Count (CBC), Flow Cytometry, and Immunophenotyping are vital CLL diagnosis tests used to assess health, detect disorders, and determine cell markers. They involve collecting samples and utilizing analysis techniques, with varying result values, prices, and interpretations. Chronic Lymphocytic Leukemia Differential Diagnosis Similar Diseases Differentiating Factors Small Lymphocytic Lymphoma Bone marrow biopsy and lymph node involvement Hairy Cell Leukemia Presence of hairy cells and associated markers Mantle Cell Lymphoma Cyclin D1 expression and characteristic t(11;14) translocation Prolymphocytic Leukemia Lymphocyte morphology, CD5 expression Acute Lymphoblastic Leukemia Blasts in peripheral blood and bone marrow Lymphoplasmacytic Lymphoma Presence of monoclonal IgM and MYD88 mutation Follicular Lymphoma Lymph node architecture and t(14;18) translocation Marginal Zone Lymphoma Lymph node architecture and specific immunophenotypic markers T-Cell Prolymphocytic Leukemia T-cell phenotype, lymphocyte morphology Splenic Marginal Zone Lymphoma Lymph node architecture, splenic involvement Chronic Lymphocytic Leukemia can be distinguished from similar diseases through factors such as lymph node involvement, presence of specific markers, cytogenetic abnormalities, and morphology. Differential diagnosis includes Small Lymphocytic Lymphoma, Hairy Cell Leukemia, Mantle Cell Lymphoma, and others. Best Doctor for Chronic Lymphocytic Leukemia Specialist Description Hematologist-Oncologist Specializes in CLL and blood cancers Medical Oncologist Expert in cancer treatment Hematopathologist Focuses on blood disorders For CLL, The best specialist is a Hematologist-Oncologist, who specializes in CLL, including blood cancers. 7 Interesting Facts of Chronic Lymphocytic Leukemia (CLL) Diagnosis CLL is often detected incidentally in routine blood tests. It is more common in older individuals. Some patients with CLL may remain asymptomatic for years. Genetic abnormalities play a role in CLL diagnosis and development. CLL is not always considered a cancer that requires immediate treatment. CLL can affect lymph nodes, bone marrow, and other organs. CLL patients may experience periods of remission and relapse. Conclusion Accurate chronic lymphocytic leukemia diagnosis is crucial in Chronic Lymphocytic Leukemia (CLL). Tests like CBC, flow cytometry, and more help determine treatment and predict outcomes. Early detection and comprehensive evaluation lead to better CLL diagnosis. Reference Chronic lymphocytic leukemia - Wikipedia [1]. Chronic Lymphocytic Leukemia - StatPearls - NCBI Bookshelf [2].
