Find out how AI has the potential to disrupt clinical trials — from patient recruitment to data collection — and how Covid-19 has catalyzed its adoption.
Use our free TrialMatch matching tool to search for clinical trials for Alzheimer's & other dementia.
What is Clinical Trail? A blog about pharmaceutical quality control, quality assurance, microbiology, production and regulatory updates provided by regulatory agencies. Pharmaceutical Guidelines.
A totally unexpected lab result has led to a prospective treatment for rheumatoid arthritis. The vaccine-based treatment proved successful in preliminary animal studies and researchers are looking to conduct more clinical trials in the future.
What is CBD oil? Does it treat Parkinson’s disease symptoms? What does the research say about it? and are there any adverse effects linked to it? Here, you will know the answers to these questions.
Learn more about a new botanical technology that is making a real difference in the herpes cases. Inquire now!
Developing innovative or repurposing drugs for orphan diseases can be rewarding, but navigating the challenges is not for the faint of heart. Expert guidance is essential in an area where patients are few; a lack of previous studies may hamper progress as you mount an orphan petition and negotiate a clinical plan with the FDA.
Posted: August 4, 20230 commentsNote: The update provided below is for informational purposes only. Any treatments described are still in ... Read More
Psychiatrists have tested the orally administered investigational medication ecopipam on adults who stutter in an open-label, uncontrolled clinical trial and found that it reduced their stuttering symptoms from the start of therapy after eight weeks of dosing. Positive results included increased speech fluency, faster reading completion, and shortened duration of stuttering events.
Smoothness, youthful radiance, firm, plump and taut skin – all skin goals that many of us hope to maintain as we age. But sometimes, in order to achieve
Background Trigger points have been shown to be active in many myofascial pain syndromes. Treatment of trigger point pain and dysfunction may be explained through the mechanisms of central and peripheral paradigms. This study aimed to investigate whether the mind/body treatment of Neuro Emotional Technique (NET) could significantly relieve pain sensitivity of trigger points presenting in a cohort of chronic neck pain sufferers. Methods Sixty participants presenting to a private chiropractic clinic with chronic cervical pain as their primary complaint were sequentially allocated into treatment and control groups. Participants in the treatment group received a short course of Neuro Emotional Technique that consists of muscle testing, general semantics and Traditional Chinese Medicine. The control group received a sham NET protocol. Outcome measurements included pain assessment utilizing a visual analog scale and a pressure gauge algometer. Pain sensitivity was measured at four trigger point locations: suboccipital region (S); levator scapulae region (LS); sternocleidomastoid region (SCM) and temporomandibular region (TMJ). For each outcome measurement and each trigger point, we calculated the change in measurement between pre- and post- treatment. We then examined the relationships between these measurement changes and six independent variables (i.e. treatment group and the above five additional participant variables) using forward stepwise General Linear Model. Results The visual analog scale (0 to 10) had an improvement of 7.6 at S, 7.2 at LS, 7.5 at SCM and 7.1 at the TMJ in the treatment group compared with no improvement of at S, and an improvement of 0.04 at LS, 0.1 at SCM and 0.1 at the TMJ point in the control group, (P < 0.001). Conclusion After a short course of NET treatment, measurements of visual analog scale and pressure algometer recordings of four trigger point locations in a cohort of chronic neck pain sufferers were significantly improved when compared to a control group which received a sham protocol of NET. Chronic neck pain sufferers may benefit from NET treatment in the relief of trigger point sensitivity. Further research including long-term randomised controlled trials for the effect of NET on chronic neck pain, and other chronic pain syndromes are recommended. Trial Registration This trial has been registered and allocated the Australian Clinical Trials Registry (ACTR) number ACTRN012607000358448. The ACTR has met the requirements of the ICMJE's trials registration policy and is an ICMJE acceptable registry.
A Phase 2 clinical trial will test the effectiveness of stem cell therapy on individuals with progressive forms of multiple sclerosis.
diaTribe is a non-profit organization providing free cutting-edge diabetes management tips from diet and exercise, to ways to avoid diabetes complications.
Beta amyloid (amyloid-β) and tau are both proteins synonymous with Alzheimer’s Disease. A clinical picture of an Alzheimer’s patient usually has to do with dead nerve cells and hardened plaques in between them. Within these
“Natural Flavors” only mean 80% natural, and they are not better or safer for you than artificial flavors. Flavors are added so that people become addicted to the processed food.
This randomised, double-blind, bicenter, placebo-controlled clinical trial investigated the effect of a daily application of 6g Kytta-Salbe® f (3×2g) …
What is it, and will it work for my child?The Lidcombe Program is an effective, evidence-based approach to the treatment of preschool stuttering.The Lidcombe Program is a direct behavioral therapy used in the treatment of children aged 3-6 who stutter. In clinical trials, the Lidcombe Program has been shown to be an effective early intervention program for stuttering. It consists of two stages: in Stage One, parents are trained in providing treatment in the home environment during daily practice
Purpose Osteoarthritis (OA) is one of the most common causes of disability and a prevalent chronic disease. The use of collagen is growing due to the satisfactory results in the treatment of OA. However, the possible beneficial effects of collagen for the treatment of OA are currently controversial. The aim of the present meta-analysis was to evaluate the effect of collagen-based supplements on OA symptoms. Methods PubMed-Medline, Scopus, and Google Scholar databases were searched for randomized placebo-controlled trials evaluating the effect of orally administered collagen on OA symptoms using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scale and/or the Visual Analog Scale (VAS). Meta-analysis was conducted using a random-effects model and a generic inverse variance method. Heterogeneity was tested using the I2 statistic index. Results Collagen treatment showed a significant reduction in the score of total WOMAC index (WMD − 8.00; 95% CI − 13.04, − 2.95; p = 0.002). After subgroup analysis of the WOMAC subscores, the collagen supplementation revealed a significant decrease in the stiffness subscore (WMD − 0.41; 95% CI − 0.74, − 0.08; p = 0.01), whereas the pain (WMD − 0.22; 95% CI − 1.58, 1.13; p = 0.75) and functional limitation (WMD − 0.62; 95% CI − 5.77, 4.52; p = 0.81) subscores did not have significant differences. Finally, a significant reduction was found in the VAS score after collagen administration (WMD − 16.57; 95% CI − 26.24, − 6.89; p
Stroke blogs provide useful information from organizations and individuals who have experienced a stroke. Here are our top 10 stroke blog choices.
Over half of all women and about 12 percent of men will experience at least one UTI in their lifetime.
Up to six in ten who received a single dose of DMT intravenously before therapy were declared depression-free three months later, in a clinical trial by Canada-based Small Pharma.
DESPERTAR DE LA CONCIENCIA Despertar de la conciencia, se refiere al momento en el que una persona se vuelve más consciente de sus pensamientos, emociones, acciones y su papel en el mundo. Es un proceso de autoconocimiento y de toma de conciencia sobre la realidad que lo rodea, lo que puede llevar a una mayor comprensión, empatía, y conexión con uno mismo y con los demás. Este despertar puede venir acompañado de un cambio de paradigma, en el que la persona ve el mundo y su vida desde una perspectiva más amplia y profunda. En un concepto intelectual; es más bien un viaje experimental hacia la esencia de tu ser, que te permite descubrir quién y qué eres realmente. Permíteme compartir contigo algunas reflexiones sobre este proceso: 1. Tomar Conciencia de Ti Mismo: El despertar es un proceso de transformación interior en el que empiezas a tomar conciencia de quién eres. Abres los ojos a una realidad que siempre ha estado ahí, pero que las distorsiones de tu mente no te permitían ver. Es como si estuvieras despertando de un sueño profundo. 2. Dejar de Sobrevivir y Empezar a Vivir: El despertar es dejar de simplemente sobrevivir y comenzar a vivir plenamente. Es un camino de evolución personal hacia tu verdadera identidad. Dejas de ser esclavo de tu mente y empiezas a escuchar los mensajes de tu alma. 3. Desaprendizaje y Soltar: El proceso de despertar implica desaprender, soltar creencias limitantes y confiar en la vida. Dejas de resistirte y comienzas a fluir con ella. Reconoces que la vida no te sucede a ti, sino que sucede para ti, para que crezcas y evoluciones. 4. Vivir en el Presente: El despertar es dejar de vivir en la ilusión mental del pasado y el futuro, y entregarte a la experiencia de la vida en el aquí y ahora. Dejas de etiquetar situaciones como problemas y las ves como oportunidades de aprendizaje. 5. Ser Auténtico y Reconocer tu Potencial Infinito: Despertar es ser auténtico, reconocer el potencial infinito que hay en ti más allá de las limitaciones de tu mente. Es reconocer tu esencia espiritual más allá de tu experiencia humana. 6. Dueño y Creador de Tu Vida: Dejas de verte como una víctima y te conviertes en dueño y creador de tu vida. Ahí reside tu poder, tu responsabilidad y tu libertad. En resumen, el despertar de la conciencia es un proceso profundo y continuo hacia la verdad y la autenticidad. Es un viaje hacia la esencia de lo que realmente eres. 🌟
Background: Bandages are commonly used to relieve pain in patients with plantar fasciitis. The goal was to compare the effects of using kinesiotape versus low-dye tape in the acute phase of plantar fasciitis on pain and comfort measures. Methods: Forty individuals with plantar fasciitis were allocated to the kinesiotape or low-dye tape interventions. The patients were assessed at baseline and every 24 h until the fifth day. The primary measure was a visual analog scale of pain. The other measures were comfort, mobility, durability, personal hygiene, sweating, and allergies. The effects were compared with an ANOVA test, 95% CI. Results: Kinesiotape was more effective in reducing pain; the greater effect occurred during the first day, with a between-group difference of 2.0 (95% CI: 1.8 to 2.2). The pain differences between the treatments progressively reduced each day from the second day. Kinesiotape offered significantly higher performance than low-dye tape in mobility, comfort, and comfort in hygiene, sweating, and durability, with a large effect size d > 0.8. Conclusions: Kinesiotape could be more effective than low-dye tape in relieving pain in patients with plantar fasciitis, with a significant clinical impact on the first day of treatment. Kinesiotape can also provide higher performance in terms of comfort.
FDA approves Inqovi, tablets for treatment of adult patients with myelodysplastic syndromes (MDS) and chronic myelomonocytic leukemia (CMML), which can be taken at home.
The U.S. Food and Drug Administration (FDA) approved Hemgenix as a one-time gene therapy for adults with hemophilia B, a condition that affects blood clotting. What is hemophilia B? Hemophilia B is a rare genetic bleeding disorder where the body makes an abnormal version of an essential clotting factor IX, or the body simply does not make enough.
Clinical Research Protocol Experts Only Social Club Cotton Tee. For the true protocol expert in your life. Features: .: Classic fit .: Made using 100% US cotton that is ethically grown and harvested. .: Certified by Oeko-Tex for safety and quality assurance.
The results of a new clinical trial show that Wegovy is linked to a reduced risk of heart attack, stroke, and heart-related death. Ozempic, a drug similar to Wegovy, had a similar clinical trial that saw a 26% reduction in cardiovascular events. Experts recommend patients looking at taking Wegovy strictly for heart health consult with a trusted healthcare professional to review their options.
What is it, and will it work for my child?The Lidcombe Program is an effective, evidence-based approach to the treatment of preschool stuttering.The Lidcombe Program is a direct behavioral therapy used in the treatment of children aged 3-6 who stutter. In clinical trials, the Lidcombe Program has been shown to be an effective early intervention program for stuttering. It consists of two stages: in Stage One, parents are trained in providing treatment in the home environment during daily practice
Breztri Aerosphere reduced COPD exarcebations better than approved therapies, and reached its primary goal in the ongoing ETHOS trial, early results show.
The amyloid theory continues to grasp at life as Eli Lilly has unveiled new phase 2 data from donanemab that show it can help Alzheimer’s disease patients by clearing these plaque | The amyloid theory continues to grasp at life as Eli Lilly has unveiled new phase 2 data from donanemab that show it can help Alzheimer’s disease patients by clearing these plaques out of the brain.
