A key energy production process that appears to be broken in the brains of GWS/ME/CFS patients could explain the cognitive problems found.
Introduction Myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) is a common, severe condition affecting 0.2 to 0.4 per cent of the population. Even so, no recent international EQ-5D based health-related quality of life (HRQoL) estimates exist for ME/CFS patients. The main purpose of this study was to estimate HRQoL scores using the EQ-5D-3L with Danish time trade-off tariffs. Secondary, the aims were to explore whether the results are not influenced by other conditions using regression, to compare the estimates to 20 other conditions and finally to present ME/CFS patient characteristics for use in clinical practice. Material and methods All members of the Danish ME/CFS Patient Association in 2013 (n=319) were asked to fill out a questionnaire including the EQ-5D-3L. From these, 105 ME/CFS patients were identified and gave valid responses. Unadjusted EQ-5D-3L means were calculated and compared to the population mean as well as to the mean of 20 other conditions. Furthermore, adjusted estimates were calculated using ordinary least squares (OLS) regression, adjusting for gender, age, education, and co-morbidity of 18 self-reported conditions. Data from the North Denmark Health Profile 2010 was used as population reference in the regression analysis (n=23,392). Results The unadjusted EQ-5D-3L mean of ME/CFS was 0.47 [0.41–0.53] compared to a population mean of 0.85 [0.84–0.86]. The OLS regression estimated a disutility of -0.29 [-0.21;-0.34] for ME/CFS patients in this study. The characteristics of ME/CFS patients are different from the population with respect to gender, relationship, employment etc. Conclusion The EQ-5D-3L-based HRQoL of ME/CFS is significantly lower than the population mean and the lowest of all the compared conditions. The adjusted analysis confirms that poor HRQoL of ME/CFS is distinctly different from and not a proxy of the other included conditions. However, further studies are needed to exclude the possible selection bias of the current study.
A study finding a concentration of unusual forms of genes could help explain the pain and other sensations found in chronic fatigue syndrome.
tratto da: La sindrome della permeabilità intestinale è una condizione in rapida crescita che colpisce milioni di persone in maniera inconsapevole. Dal nome, si potrebbe pensare che la sindrome de…
A schedule of events for May 12 International ME/CFS and FM Awareness Day 2015.
Once dismissed by many doctors as a psychological illness, new research suggests CFS has its roots in infection – and there is hope of successful treatment
Brains of people with POTS have diminished white and gray matter.
Early studies suggest a nerve condition called small fiber neuropathy could change how the medical profession views fibromyalgia and perhaps ME/CFS
An immune factor identified in ME/CFS patients is associated with cognitive decline and reduced neurogenesis.
La sindrome da stanchezza cronica (Chronic Fatigue Syndrome) è un disturbo dalle origine ancora oscure, caratterizzato da una stanchezza prolungata e debilitante, e da multipli sintomi non specifici, quali cefalea, mal di gola ricorrente, dolori muscolari e alle ossa, disturbi del sonno, perdita di memoria, difficoltà di concentrazione e da un malessere generale. I sintomi per […]
The comments came from the Institute of Medicine, a prestigious US government advisory group. Yesterday it announced five main symptoms as simple criteria for doctors to use in making a diagnosis.
Un nuovo studio trova che nei pazienti affetti da stanchezza cronica vi sono delle anomalie cerebrali. Queste evidenti differenze nel cervello dei pazienti con…
Exercise caused increased blood oxygenation level dependent activation of midbrain, Rolandic operculum and other regions in myalgic encephalomyelitis/chron
This is a guest post by Robert Wall from Untitled Minimalism . It's the first post in my new occasional series, Stories of Transformation. I never wanted to be a minimalist. I actually liked my stuff. In fact, I liked it so much that I had huge piles of it at five different addresses. I had a
An estimated 1 million Americans are debilitated by the condition, which isn't well understood by the medical community. Advocates and patients argue this is in part due to a continued stigma caused by its unserious-sounding name.
