Outstanding Promise. Ketamine has been around for many years, firstly as a dissociative anaesthetic and then as a psychedelic drug. But it might become best known for it's powerful antidepressant properties (Berman et al 2000; Zarate et al 2006). Compared … Continue reading →
A new article in The Atlantic does some impressive cherry-picking of student opinion.
The behavior of lymphocytes in the immune system depends on encounters with antigens. These bind to immunoreceptors on the surface of T-cells and B-cells, activating a variety of signal transduction pathways that control cell survival, proliferation, differentiation, and effector functions. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology includes contributions covering the structures of the T-cell and B-cell immunoreceptors, the numerous kinases and adaptors that associate with their intracellular tails, and the downstream signaling pathways that lead to transcription of interleukins and other outputs. Other contributions examine the roles of other receptors, co-stimulatory signals, and innate immune responses in regulation of immunoreceptor signaling. The spatial organization of the immunological synapses connecting lymphocytes and antigen-presenting cells is also discussed, along with the role of the cytoskeleton in immunoreceptor function. Computational models of the signaling processes complete the volume, making it essential reading for systems biologists as well as all immunologists and cell biologists interested in understanding how lymphocytes function.
Obesity leads to cognitive impairment by activating microglial cells, which consume otherwise functional synapses in the hippocampus, according to a study of male mice.
College and university presidents overwhelmingly describe race relations on their campus as excellent or good, are increasingly upbeat about their institutions' financial situations, give President Obama's higher education record a grade of C, and generally dismiss the push to hire campus leaders with nonacademic backgrounds.
Arizona's chaotic primary election demonstrates what’s bound to happen in light of the now-gutted federal Voting Rights Act.
The former Antony And The Johnsons singer's first solo album combines dance beats with a stark look at global strife. "Raising your voice is the antidote to a sense of powerlessness," she says.
Photographer Tadao Cern spent a weekend photographing people as they slept on a public beach in Lithuania. The art project, entitled Comfort Zone, aims to explore how different surroundings can affect people's behaviour and inhibitions
The benefits of mindfulness meditation just keep piling up.
The concept of ‘the one’ is not rooted in love, it is rooted in a desire, much like most of everything else we do, to be saved from ourselves. The idea that there is a perfect love that will induce…
A study reveals that attractive food packaging leads consumers to eat more than the suggested size. Moreover, the images on the box is more than the actual recommended serving size.
The largest-ever survey of social class, conducted by the BBC, suggests there are now seven social classes in the UK.
EPSP/IPSP + Temporal Summation + Spatial Summation
Do you struggle to prioritize your own needs in relationships? Read this.
Many life experiences, such as witnessing the birth of a child or finally achieving a long sought-after goal, can lead to what may seem like confusing expressions of emotion, like tears of joy. But new …
Bobby Seale looking over bags of food being donated to the black community.
This image from the Hubble Space Telescope uses 11 filters to allow an unprecedented wide-spectrum view of the intermediate universe.
The Department of Education is recognizing that college attainment should be defined by what students learn, not time spent at traditional institutions.
Practical ways of maintaining your Reiki healer vibration in the daily life: awareness, acceptance, surrender.
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