Handwashing is the most effective way to prevent the spread of illness according to the Centers for Disease Control and Prevention. How to Wash Your Hands Wet hands (Mójese las manos) Apply Soap (Aplique jabón) Scrub for 20 seconds (Frótese las manos por 20 segundos) Rinse (Enjuáguese) Dry (Séquese las manos) Turn Off Water with Paper Towel (Cierre el grifo usando una toalla de papel)