What Is Basal Cell Carcinoma (BCC)? Basal cell carcinoma (BCC) is the most common form of cancer, with about a million new cases estimated in the U.S. each year. It is rarely a threat to life. Basal cells line the deepest layer of the epidermis. Basal cell carcinomas are malignant growths–tumors–that arise in this layer. Get expert treatment for basal cell carcinoma at Advanced Dermatology PC. Our specialized approach ensures the best care for skin cancer patients.