December 21, 2017 by Tristan Horrom, Veterans Affairs Research Richard Hutton, a patient at the Parkinson's Disease Research, Education, and Clinical Center at the Corporal Michael J. Crescenz VA Medical Center in Philadelphia, underwent deep brain stimulation back in 2009. Here, he gets checked by Dr. Meredith Spindler. Credit: Tommy Leonardi A treatment called deep brain stimulation (DBS) could extend the life of people with Parkinson's disease. Researchers at the Edward Hines, Jr. VA Hospital in Illinois found that patients who received stimulation via an implanted device had a modest survival advantage compared with those treated with medication only. The results appeared in the Nov. 18, 2017, issue of Movement Disorders. Previous studies have shown that DBS can improve motor function in people with Parkinson's disease. The treatment involves electrodes surgically inserted into specific areas of the brain. An impulse generator battery—similar to what is used in pacemakers—is also implanted, under the collarbone or in the abdomen. The battery creates electrical impulses that the electrodes deliver to the brain tissue. Dr. Frances Weaver, lead author on the study, explained the benefit of DBS: "Overall, DBS surgery has been viewed quite positively by both patients and providers. There is an immediate effect on patients who have DBS on their motor function—the dyskinesia [involuntary muscle movements] is either gone or greatly reduced. The patient can move around and do things they hadn't been able to." While deep brain stimulation may improve function compared with those who do not receive it, little evidence exists on whether the treatment has any benefits to life expectancy. To answer that question, the researchers looked at data for 611 Veterans with Parkinson's disease who had a deep brain stimulation device implanted. They compared this with data on 611 Veterans with Parkinson's but without the device. The data came from VA and Medicare administrative files from between 2007 and 2013. The researchers found that patients treated with deep brain stimulation survived an average of 6.3 years after the surgery, versus 5.7 years for the non-DBS patients after the date they might have gotten surgery based on their match to a surgery patient—a difference of eight months. The researchers had paired each DBS patient with a clinically and demographically similar non-DBS patient—for example, in terms of age and symptom severity—and tracked survival from the date when surgery either took place, for the DBS group; or might have theoretically taken place, for the non-DBS group. The average age of veterans in the study was 69, reflecting the higher prevalence of Parkinson's among older people. The older age of the study group could have led to more deaths from age-related conditions, but the researchers point out that a majority of the causes of death for those who died during the study period were related to Parkinson's disease. While the survival edge in the DBS group is modest, the researchers point out that quality of life is also improved following DBS, mostly because the treatment can help control symptoms such as tremors and rigidity. While the results suggest that deep brain stimulation could improve survival rates for patients with Parkinson's disease, the researchers note a few limitations to the study. They explain that it is possible that deep brain stimulation patients were healthier than their counterparts in the medication-only group. Patients with the implanted surgical device were more likely to have been monitored closely, so other chronic conditions may have been diagnosed and treated earlier. The study group was also mostly male—because the veteran population is majority male—meaning that the results cannot necessarily be generalized to women with Parkinson's disease. Parkinson's disease is a neurodegenerative disorder. It affects neurons in the brain that produce dopamine. Its cause is currently unknown, and so far there is no cure. Parkinson's itself is not fatal, but complications related to the disease often lead to death. Common symptoms of Parkinson's disease include tremor, slowness of movement, limb rigidity, and walking and balance problems. People with Parkinson's disease have a shorter life expectancy than those without the disease. While medication can manage symptoms of the disease, it has not been shown to improve survival for those with Parkinson's. As Weaver explains, patients usually undergo DBS surgery when the medication is no longer effective. "The surgery may get patients back to where they were when the medication was effective. That is, DBS is typically as effective as the medication—if the medication was still working," she says. The researchers believe that more research is warranted into whether DBS can extend life expectancy in Parkinson's disease. It remains unclear whether the treatment modifies the actual disease, or just helps control the related conditions that may shorten life. According to Weaver, the improved quality of life after DBS may improve survival. It is also possible that the ongoing monitoring required with DBS means that patients are getting more medical attention in general, leading to better care. More research is needed to see what direct effect DBS has on neuroplasticity or brain function. Provided by: Veterans Affairs Research https://medicalxpress.com/news/2017-12-deep-brain-linked-longer-survival.html

December 21, 2017 by Tristan Horrom, Veterans Affairs Research Richard Hutton, a patient at the Parkinson's Disease Research, Education, and Clinical Center at the Corporal Michael J. Crescenz VA Medical Center in Philadelphia, underwent deep brain stimulation back in 2009. Here, he gets checked by Dr. Meredith Spindler. Credit: Tommy Leonardi A treatment called deep brain stimulation (DBS) could extend the life of people with Parkinson's disease. Researchers at the Edward Hines, Jr. VA Hospital in Illinois found that patients who received stimulation via an implanted device had a modest survival advantage compared with those treated with medication only. The results appeared in the Nov. 18, 2017, issue of Movement Disorders. Previous studies have shown that DBS can improve motor function in people with Parkinson's disease. The treatment involves electrodes surgically inserted into specific areas of the brain. An impulse generator battery—similar to what is used in pacemakers—is also implanted, under the collarbone or in the abdomen. The battery creates electrical impulses that the electrodes deliver to the brain tissue. Dr. Frances Weaver, lead author on the study, explained the benefit of DBS: "Overall, DBS surgery has been viewed quite positively by both patients and providers. There is an immediate effect on patients who have DBS on their motor function—the dyskinesia [involuntary muscle movements] is either gone or greatly reduced. The patient can move around and do things they hadn't been able to." While deep brain stimulation may improve function compared with those who do not receive it, little evidence exists on whether the treatment has any benefits to life expectancy. To answer that question, the researchers looked at data for 611 Veterans with Parkinson's disease who had a deep brain stimulation device implanted. They compared this with data on 611 Veterans with Parkinson's but without the device. The data came from VA and Medicare administrative files from between 2007 and 2013. The researchers found that patients treated with deep brain stimulation survived an average of 6.3 years after the surgery, versus 5.7 years for the non-DBS patients after the date they might have gotten surgery based on their match to a surgery patient—a difference of eight months. The researchers had paired each DBS patient with a clinically and demographically similar non-DBS patient—for example, in terms of age and symptom severity—and tracked survival from the date when surgery either took place, for the DBS group; or might have theoretically taken place, for the non-DBS group. The average age of veterans in the study was 69, reflecting the higher prevalence of Parkinson's among older people. The older age of the study group could have led to more deaths from age-related conditions, but the researchers point out that a majority of the causes of death for those who died during the study period were related to Parkinson's disease. While the survival edge in the DBS group is modest, the researchers point out that quality of life is also improved following DBS, mostly because the treatment can help control symptoms such as tremors and rigidity. While the results suggest that deep brain stimulation could improve survival rates for patients with Parkinson's disease, the researchers note a few limitations to the study. They explain that it is possible that deep brain stimulation patients were healthier than their counterparts in the medication-only group. Patients with the implanted surgical device were more likely to have been monitored closely, so other chronic conditions may have been diagnosed and treated earlier. The study group was also mostly male—because the veteran population is majority male—meaning that the results cannot necessarily be generalized to women with Parkinson's disease. Parkinson's disease is a neurodegenerative disorder. It affects neurons in the brain that produce dopamine. Its cause is currently unknown, and so far there is no cure. Parkinson's itself is not fatal, but complications related to the disease often lead to death. Common symptoms of Parkinson's disease include tremor, slowness of movement, limb rigidity, and walking and balance problems. People with Parkinson's disease have a shorter life expectancy than those without the disease. While medication can manage symptoms of the disease, it has not been shown to improve survival for those with Parkinson's. As Weaver explains, patients usually undergo DBS surgery when the medication is no longer effective. "The surgery may get patients back to where they were when the medication was effective. That is, DBS is typically as effective as the medication—if the medication was still working," she says. The researchers believe that more research is warranted into whether DBS can extend life expectancy in Parkinson's disease. It remains unclear whether the treatment modifies the actual disease, or just helps control the related conditions that may shorten life. According to Weaver, the improved quality of life after DBS may improve survival. It is also possible that the ongoing monitoring required with DBS means that patients are getting more medical attention in general, leading to better care. More research is needed to see what direct effect DBS has on neuroplasticity or brain function. Provided by: Veterans Affairs Research https://medicalxpress.com/news/2017-12-deep-brain-linked-longer-survival.html

This recipe for the Perfect Oven Pot Roast, in fact, is the perfect meal. The meat is slow cooked in the oven with carrots and onions until the meat is fall-apart-tender and the carrots are tender crisp.

Our Beef Chuck Roast is braised slowly to create a wonderfully tender and flavorful meal!

The perfect 7 day Big Island itinerary! This day-by-day guide for how to spend one week in Hawaii with the best things to see and do.

Hier findest du 25 Rezepte für die Heißluftfritteuse. Schnapp dir deinen Air Fryer und probier dich durch!

With just a few simple ingredients, you can create beautiful and delicious charcuterie boards for beginners that everyone will love.

You can easily enjoy more healthy dinners on your low carb diet with these amazing low carb high protein meals. These high protein meal ideas are perfect to help you eat more nutritiously on your weight loss journey.

Gordon Ramsay's shepherd's pie is a great British recipe. The filling for the pie is made with meat, vegetables, sauces, and spices. It is then topped with a mash and cheese. Check out the article to make your own shepherd's pie.

A round-up of easy healthy acid-reflux friendly dinner recipes to keep you eating well with a happy stomach every night of the week!

Wer ein Low Carb Abendessen schnell zubereiten will, sollte diese Rezepte zum Abnehmen in den Speiseplan einbauen. Egal ob vegetarisch, mit Fleisch, mit Fisch, kalt oder warm: Wir zeigen dir die besten Low Carb Rezepte für ein Abendessen ohne Kohlenhydrate.

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You can make crispy southern fried okra from scratch.

Are you ready to fall in love with the Ninja Foodi? These 65 Easy Ninja Foodi Recipes will help you get started cooking with the Ninja Foodi.

Forget store bought tortillas, and make your own with this flour tortilla recipe. This homemade tortilla recipe can be easily doubled or tripled if you wanted to make larger batches, and they freeze perfectly!

Check out the best things to do in Maui! Looking to discover the beauty of the Valley Isle? These amazing Maui activities will blow your mind.