Updated August 2023 (see end of post for update) I am a birth educator. I also have a PhD in physiology of reproduction, and 20 years of research
It is widely believed that during the relatively short duration of a normal pregnancy the placenta progressively ages and is, at term, on the verge of a decline into morphological and physiological senescence.1-3 This belief is based on the apparent convergence of clinical, structural, and functional data, all of which have been taken, rather uncritically, as supporting this concept of the placenta as an aging organ with, all too often, no distinction being made between time related changes and true aging changes. I will review some of these concepts and consider whether the placenta truly undergoes an aging process. For the purposes of this review an aging change is considered to be one which is intrinsic, detrimental, and progressive and which results in an irreversible loss of functional capacity, an impaired ability to maintain homeostasis, and decreased ability to repair damage. The placenta is unusual in so far as its basic histological structure undergoes a considerable change throughout its lifespan. For some time it has been customary to describe the appearances of the placental villi in terms of their changing appearance as pregnancy progresses, comparing, for instance, typical first trimester villi with those in third trimester placentas. It has often been implied that this changing appearance is an aging process, but it is now recognised that this temporal variability in villous appearances reflects the continual development and branching of the villous tree (fig 1) In recent years the relation between the growth of the villous tree and the villous histological appearances has been formally codified5-8with identification of five types of villi (fig 2). Figure 1 Diagrammatic representation of a peripheral villous tree, showing a large central stem villus: the lateral branches from this are the mature intermediate villi from which the terminal villi protrude. Figure 2 Representation of the peripheral …
Sara Wickham recommends a resource discussing the myth of the aging placenta and adds her own thoughts to the discussion.
It was as a pupil at Wolverhampton Grammar School1that Robert William Felkin met the explorer David Livingstone, who inspired him with his tales of Africa. And when he met A M Mackay, a medical missionary from Uganda, in London in 1877 at the age of 24, he became determined to visit Africa. By 1875 he had become a medical student at Edinburgh University, but before completing his training, he was sent to Uganda in 1878 by the Church Missionary Society. He travelled up the Nile to Khartoum, where he met General Gordon, and then on through what was then wild and unmapped country to the Great Lakes. There he met Emin Pasha, the Governor of the Equatorial Province, and was presented to King M’tesa, whose personal physician he became in 1879. When a Muslim anti-missionary movement threatened the lives of his fellow Christians, Felkin warned the King that, should any harm come to them, a great disaster would befall his people. As a sign he foretold that the sun would be darkened; in due course the anticipated eclipse occurred and Felkin was established as a great “medicine man.” During his stay in Uganda he studied the local diseases and also undertook anthropological measurements of the pygmies. Of particular interest, though, were his studies on childbirth. In 1880 he returned down the Nile and on to England in the company of envoys of King M’tesa to Queen Victoria. Later that year he returned to Africa, travelling widely but spending most of his time in Zanzibar where he actively campaigned against the slave trade. In 1881 he returned to Edinburgh to complete his medical studies (LRCP, LRCS,Ed, 1884). While still a medical student he became a Fellow of …
Updated August 2023 (see end of post for update) I am a birth educator. I also have a PhD in physiology of reproduction, and 20 years of research
Placenta encapsulation is gaining popularity and press so this episode is entirely about myths that come along with the ingestion of placentas. There are many benefits that people find from placenta ingestion. I am not a placenta expert, so today we will hear from Jade Hillery about all the things p
Many of the pregnancy "facts" you think you know aren't actually backed up by science. Here, we debunk the most common pregnancy myths
Updated August 2023 (see end of post for update) I am a birth educator. I also have a PhD in physiology of reproduction, and 20 years of research