Section I. Background 1 Epidemiology of Oral Cavity Cancer 2 Patient Populations at Increased Risk for Oral Cavity Cancer Section II. Premalignancies of the Oral Cavity 3 Premalignant Oral Lesions 4 Management of Oral Premalignant Lesions Section III. Diagnostic Evaluation of Oral Cavity Cancers 5 Evaluation and Staging for Cancers of the Oral Cavity 6 Photographic Documentation of the Oral Cavity 7 Imaging of Oral Cavity Cancers 8 Pathology and Cytopathology: Oral Malignant Mucosal Neoplasms 9 Pathology: Oral Cavity Salivary Gland Malignancies Section IV. Pretreatment Considerations 10 Pretreatment Dental Evaluation 11 Pretreatment Speech-language Pathology Evaluation 12 Nutrition for Oral Cancer Patients Section V. Evaluation and Surgical Management of Subsite-specific Oral Squamous Cell Cancers 13 Squamous Cell Cancer of the Lip 14 Reconstruction of the Lip 15 Squamous Cell Cancer of the Oral Tongue 16 Reconstruction of the Oral Tongue 17 Squamous Cell Cancer of the Floor of Mouth 18 Floor of Mouth Reconstruction 19 Squamous Cell Cancer of the Buccal Mucosa 20 Buccal Reconstruction 21 Squamous Cell Cancer of the Alveolar Ridge 22 Reconstruction of Alveolar Ridge 23 Squamous Cell Cancer of Retromolar Trigone 24 Reconstruction of the Retromolar Trigone 25 Squamous Cell Cancer of the Palate 26 Reconstruction of the Palate 27 Malignant Tumors of the Mandible 28 Reconstruction of Mandibular Defects 29 Primary Malignancies of the Maxilla 30 Reconstruction of the Maxilla 31 Reconstruction of Multisite Defects 32 Neck Management for Oral Malignancies 33 Definitive External Beam Radiotherapy for Oral Cavity Cancer 34 Brachytherapy for Oral Cavity Cancer Section VI. Adjuvant Therapeutic Considerations 35 Adjuvant Radiotherapy for Oral Cavity Cancer 36 Adjuvant Chemotherapy/Novel Therapeutics Section VII. Management of Nonsquamous Cell Cancers of the Oral Cavity 37 Oral Cavity Salivary Gland Malignancies (Sublingual and Minor) 38 Uncommon Oral Cavity Malignancies Section VIII. Posttreatment Considerations 39 Oral Rehabilitation 40 Complications of Oral Cancer Surgery 41 Radiotherapy Related Side Effects in the Treatment of Oral Cavity Malignancies 42 Psychosocial Rehabilitation of Oral Cancer Patients 43 Posttreatment Surveillance 44 Posttreatment Speech-language Pathology 45 Posttreatment Dental Considerations 46 Oral and Dental Complications of Oral Cancer Treatment 47 Trismus in the Head and Neck Cancer Patient Section IX. Considerations for Recurrent and Metastatic Oral Cavity Cancers 48 Management of Locoregional Recurrent Oral Cavity Cancers 49 Management of Metastatic Oral Cavity Cancers 50 Immunotherapy 51 Palliative Care/Considerations for Metastatic Oral Cavity Cancers Section X. Future Directions 52 Cancer Prevention and Oral Preneoplasia.