Nioxin Pro System 2 is designed for natural, untreated hair with progressed thinning. Clinically and dermatologically tested, this shampoo nourishes and gently cleanses your hair to prevent against follicle-clogging sebum, resulting in thicker, fuller hair.  • Formulated with a powerful blend of niacinamide, biotin and caffeine to help nourish the hair root, stimulate hair follicles and strengthen the hair. • The three-step regimen begins with the Scalp + Hair Shampoo. Start by applying it to wet hair, gently massaging it into the scalp and hair for one minute before rinsing thoroughly. • This gentle cleanser works to remove buildup, including follicle-clogging sebum and environmental residues, preparing the scalp for the next steps. How to use:Apply shampoo to scalp and massage evenly. Rinse thoroughly.